| 產(chǎn)品編號(hào) | bs-5875R |
| 英文名稱 | MMP-23 Rabbit pAb |
| 中文名稱 | 基質(zhì)金屬蛋白酶23抗體 |
| 別 名 | Cysteine array matrix metalloproteinase; Femalysin; Matrix metallopeptidase 21; Matrix metallopeptidase 23B; Matrix metalloproteinase 22; Matrix metalloproteinase 23; Matrix metalloproteinase 23B; Matrix metalloproteinase in the female reproductive tract; |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 細(xì)胞骨架 細(xì)胞外基質(zhì) 泛素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 36/44 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MMP-23: 281-380/390 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Matrix Metalloproteinase 23 is a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region.
Function: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity). Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein (By similarity). Membrane; Single-pass type II membrane protein. Note=A secreted form produced by proteolytic cleavage may also exist (Probable). Tissue Specificity: Predominantly expressed in ovary, testis and prostate. Post-translational modifications: N-glycosylated. Proteolytic cleavage might yield an active form (By similarity). Similarity: Belongs to the peptidase M10A family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. SWISS: O75900 Gene ID: 8510 Database links: Entrez Gene: 8510 Human Entrez Gene: 26561 Mouse Omim: 603321 Human SwissProt: O75900 Human SwissProt: O88676 Mouse Unigene: 192316 Human Unigene: 671760 Human Unigene: 29373 Mouse Unigene: 22562 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human A549 cell lysates
Lane 2: Human Hela cell lysates
Lane 3: Human Jurkat cell lysates
Lane 4: Human A431 cell lysates
Lane 5: Human Jurkat cell lysates
Primary: Anti-MMP-23 (bs-5875R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 36/44 kD
Observed band size: 44 kD
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